Your browser is too old for this site to support. Please upgrade to FireFox, Chrome, or Safari

Compute the Cure logo

The Open Genomics Engine (OpenGE) is an open source project for analyzing and interpreting high-throughput sequencing data. The framework is free, easy to install and use; and enables comparative analysis of cancer genomes. OpenGE is extensible and supports the management of analysis pipelines composed of existing tools. Furthermore, OpenGE includes newly developed and modified versions of existing tools that have been optimized for parallel processing on CPUs and GPUs to maximize performance on commodity hardware.

The software is currently available as binaries for Linux and Mac OS, or as source. Future releases will include VMWare and Amazon EC2 images.

The mission of OpenGE is to advance cancer genomics by streamlining and accelerating the analysis of genomes for the cancer research community.

Download OpenGE.

Learn more Join our mailing list

What’s New

OpenGE version 0.4 – Now Available

We are pleased to release OpenGE 0.4 which now features improved speed and stability…

Read Article

OpenGE at Bio-IT World

David Mittelman from the OpenGE development team will be presenting “A Comprehensive Map of Microsatellite Repeat Variation
in Human Genomes”…

Read Article

OpenGE version 0.3 – Now Available

We are proud to release the latest build of OpenGE, version 0.3, which now features a workflow manager and…

Read Article
View All
StanfordMedicine_no shield_web

Dr. Hanlee Ji from Stanford Medicine is using Open Genomics Engine to support efficient, accurate and rapid analysis of cancer genome sequences.

Dr. Hanlee Ji from Stanford Medicine is using Open Genomics Engine to support efficient, accurate and rapid analysis of cancer genome sequences.

Livestrong-Logo

The future of cancer therapy and personalized treatment ultimately means more survivors. If we can more quickly sequence a patient’s DNA, more targeted information can be taken into account when therapy is developed and delivered…

— Doug Ulman, CEO, Livestrong
“
”

The future of cancer therapy and personalized treatment ultimately means more survivors. If we can more quickly sequence a patient’s DNA, more targeted information can be taken into account when therapy is developed and delivered. That personalized piece is on the cusp of significant progress and we believe the Open Genomics Engine could help to accelerate the time it takes for researchers to make these discoveries.

— Doug Ulman, CEO, Livestrong
“
”
VT-Testimonial-Logo

There is a need to more quickly identify changes in the genome, and computing plays a critical role in speeding this process. Our hope is that Open Genomics Engine…helps us move faster towards a cure…

— Dennis Dean, Director of Life Sciences, Virginia Tech
“
”

Open Genomics Engine was developed to be a comprehensive open source framework for analyzing and interpreting high-throughput sequencing data. There is a need to more quickly identify changes in the genome, and computing plays a critical role in speeding this process. Our hope is that Open Genomics Engine becomes a valuable resource for the cancer research community and helps us move faster towards a cure.

— Dennis Dean, Director of Life Sciences, Virginia Tech
“
”
View All